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Caries Res. 2011;45(2):162-73. doi: 10.1159/000327374. Epub 2011 Apr 27.

The effect of chlorhexidine varnish on root caries: a systematic review.

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1
Department of Periodontology, Academic Centre for Dentistry Amsterdam, University of Amsterdam, The Netherlands. d.slot@acta.nl

Abstract

OBJECTIVE:

The aim of this study was to systematically review the present literature on the effect of chlorhexidine varnish (CHX-V) on root caries.

MATERIALS AND METHODS:

The MEDLINE-PubMed, the Cochrane-CENTRAL and EMBASE databases were searched through December 2010 to identify any appropriate studies. Root caries incidence and root caries activity were selected as outcome variables.

RESULTS:

An independent screening of the unique titles and abstracts of 24 MEDLINE-PubMed, 14 Cochrane-CENTRAL and 18 EMBASE papers resulted in 6 publications that met the eligibility criteria. Data extraction provided no conclusive evidence that the application of CHX-V is effective in patients when regular professional oral prophylaxis is performed. If effective, the 40% CHX-V was found to provide a benefit over a control or fluoride varnish. CHX-V at lower concentrations (1 and 10%) may provide protection against root caries in high-risk patients (such as geriatric and xerostomia patients) in the absence of regular professional oral prophylaxis.

CONCLUSION:

Within the limitations of this review, it may be concluded that in the absence of regular professional tooth cleaning and oral hygiene instructions, CHX-V may provide a beneficial effect in patients in need of special care. The strength of this recommendation is graded as 'weak'.

PMID:
21525751
DOI:
10.1159/000327374
[Indexed for MEDLINE]
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