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J Am Chem Soc. 2011 May 18;133(19):7571-6. doi: 10.1021/ja201634d. Epub 2011 Apr 27.

Rapid identification of bacteria with a disposable colorimetric sensing array.

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Department of Applied Chemistry, National University of Kaohsiung, 700 Kaohsiung University Road, Kaosiung 811, Taiwan.


Rapid identification of both species and even specific strains of human pathogenic bacteria grown on standard agar has been achieved from the volatiles they produce using a disposable colorimetric sensor array in a Petri dish imaged with an inexpensive scanner. All 10 strains of bacteria tested, including Enterococcus faecalis and Staphylococcus aureus and their antibiotic-resistant forms, were identified with 98.8% accuracy within 10 h, a clinically important time frame. Furthermore, the colorimetric sensor arrays also proved useful as a simple research tool for the study of bacterial metabolism and as an easy method for the optimization of bacterial production of fine chemicals or other fermentation processes.

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