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Hum Vaccin. 2011 Jul;7(7):757-61. doi: 10.4161/hv.7.7.15576. Epub 2011 Jul 1.

Effectiveness of rotavirus vaccination in Spain.

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Área de Pediatría, Hospital Clínico Universitario de Santiago de Compostela, Spain.


With the aim of determining rotavirus vaccine effectiveness (RVVE) in Spain, from Oct-2008/Jun-2009, 467 consecutive children below 2 years old with acute gastroenteritis (AGE) were recruited using a pediatric research network ( that includes primary, emergency and hospital care settings. Of 467 enrolled children, 32.3% were rotavirus positive and 35.0% had received at least one dose of any rotavirus vaccine. RRVE to prevent any episode of rotavirus AGE was 91.5% (95% CI: 83.7%-95.6%). RVVE to prevent hospitalization by rotavirus AGE was 95.6% (85.6-98.6%). No differences in RVVE were found regarding the vaccine used. Rotavirus vaccines have showed an outstanding effectiveness in Spain.

[Indexed for MEDLINE]

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