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Jpn J Radiol. 2011 Apr;29(3):212-6. doi: 10.1007/s11604-010-0523-0. Epub 2011 Apr 26.

Serial computed tomography and magnetic resonance imaging findings of biphasic acute hemorrhagic leukoencephalitis localized to the brain stem and cerebellum.

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Department of Radiology, Ilsan Paik Hospital, Inje University School of Medicine, 2240 Daehwa-dong, Ilsanseo-gu, Goyang-si, Gyeonggi-do 411-706, Korea.


Acute hemorrhagic leukoencephalitis (AHL) is a rare and usually fatal disease characterized by an acute onset of neurological abnormalities. We describe the case of a 37-year-old man with biphasic AHL with a focus on the rare involvement of the brain stem and cerebellum. Initial computed tomography (CT) and magnetic resonance imaging revealed two hemorrhagic foci in the left middle cerebellar peduncle. After 15 days multifocal hematomas in the contralateral cerebellar hemisphere were imaged using CT. The pathological diagnosis was AHL. Following high-dose steroid treatment, the patient recovered with minor neurological sequelae.

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