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Eur J Epidemiol. 2011 Jul;26(7):557-61. doi: 10.1007/s10654-011-9582-5. Epub 2011 Apr 26.

GEIRA: gene-environment and gene-gene interaction research application.

Author information

1
Institute of Environmental Medicine, Karolinska Institutet, SE-171 77, Box 210, Stockholm, Sweden. Bo.Ding@ki.se

Abstract

The GEIRA (Gene-Environment and Gene-Gene Interaction Research Application) algorithm and subsequent program is dedicated to genome-wide gene-environment and gene-gene interaction analysis. It implements concepts of both additive and multiplicative interaction as well as calculations based on dominant, recessive and co-dominant genetic models, respectively. Estimates of interactions are incorporated in a single table to make the output easily read. The algorithm is coded in both SAS and R. GEIRA is freely available to non-commercial users at http://www.epinet.se. Additional information, including user's manual and example datasets is available online at http://www.epinet.se.

PMID:
21519893
PMCID:
PMC3143319
DOI:
10.1007/s10654-011-9582-5
[Indexed for MEDLINE]
Free PMC Article

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