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Clin Exp Optom. 2011 Nov;94(6):592-4. doi: 10.1111/j.1444-0938.2011.00618.x. Epub 2011 Apr 25.

Limbal stem cell disease: management with scleral lenses.

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  • 1Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota 55905, USA.



Limbal stem cell deficiency (LSCD) results from damage to or destruction of corneal stem cells.


A retrospective review of clinical records of a patient with LSCD describes the use of scleral lenses in disease management.


A patient presented with a one-year history of clinically diagnosed LSCD, which was worsening despite aggressive topical and systemic medical therapy. The condition resolved rapidly with initiation of scleral lens wear. The integrity of the ocular surface was maintained for 18 months even after the cessation of lens wear.


Scleral lenses might allow some patients with LSCD to delay or avoid more aggressive surgical intervention.

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