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Phys Rev Lett. 2011 Apr 1;106(13):138104. Epub 2011 Apr 1.

Analytical description of extension, torque, and supercoiling radius of a stretched twisted DNA.

Author information

1
CNRS, UMR 7190, Institut Jean Le Rond d'Alembert, F-75005 Paris, France.

Abstract

We study the mixture of extended and supercoiled DNA that occurs in a twisted DNA molecule under tension. Closed-form asymptotic solutions for the supercoiling radius, extension, and torque of the molecule are obtained in the high-force limit where electrostatic and elastic effects dominate. We demonstrate that experimental data obey the extension and torque scaling laws apparent in our formulas, in the regime where thermal fluctuation effects are quenched by applied force.

PMID:
21517425
PMCID:
PMC3120040
DOI:
10.1103/PhysRevLett.106.138104
[Indexed for MEDLINE]
Free PMC Article

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