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Curr Biol. 2011 Apr 26;21(8):R288-90. doi: 10.1016/j.cub.2011.03.010.

Oogenesis: when most is good enough.

Author information

1
Stowers Institute for Medical Research, 1000 E. 50th Street, Kansas City, MO 64110, USA. rsh@stowers.org

Abstract

In male meiosis an unaligned chromosome blocks meiotic progression. However, oocytes with one or more misaligned chromosomes can complete meiosis. This difference reflects a more permissive role of the spindle assembly checkpoint, rather than solely reflecting the ability of some univalents to adopt a meiosis II-like orientation on the spindle.

PMID:
21514514
DOI:
10.1016/j.cub.2011.03.010
[Indexed for MEDLINE]
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