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Bull Acad Natl Med. 2010 Jun;194(6):903-11; discussion 911-2.

[Fetal pain: immediate and long term consequences].

[Article in French]

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Pô1e d'Obstétrique, Hôpital Jeanne de Flandre, CHRU de Lille 59037 Lille.


Several situations are potentially painful for fetuses, such as malformations and invasive procedures. Nociceptive pathways are known to be functional at 26 weeks. Even if it is not possible to evaluate the fetal experience of pain, it is essential to examine its immediate and long-term consequences. As early as the beginning of the second trimester, hemodynamic and hormonal responses are observed following fetal nociceptive stimulation, In experimental studies, long-term changes have been noted in the corticotrop axis, subsequent responses to pain, and behavior after perinatal nociceptive stimulation.

[Indexed for MEDLINE]

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