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Heart Lung Circ. 2011 May;20(5):318-24. doi: 10.1016/j.hlc.2011.02.003.

Coronary artery bypass grafting with and without manipulation of the ascending aorta--a meta-analysis.

Author information

1
Cardiothoracic Surgical Unit, Royal Prince Alfred Hospital, Sydney, Australia. jjbedelman@gmail.com

Abstract

BACKGROUND:

The main criticism of surgery in the SYNTAX trial was increased rate of stroke when compared to percutaneous coronary intervention. We aimed to determine whether avoiding aortic manipulation would decrease the rate of stroke.

METHOD:

We performed a meta-analysis of seven studies comparing coronary artery bypass grafting (CABG) with and without manipulation of the ascending aorta.

RESULTS:

When anaortic off-pump coronary artery bypass grafting (OPCAB) was compared with conventional CABG, the rate of stroke was 0.38% vs. 1.87% (p<0.0001). When anaortic OPCAB was compared with OPCAB using a side-clamp or proximal graft anastomosis device the rate of stroke was 0.31% vs. 1.35% (p=0.003).

CONCLUSION:

Avoiding aortic manipulation during CABG may decrease the rate of peri-operative stroke.

Comment in

PMID:
21511187
DOI:
10.1016/j.hlc.2011.02.003
[Indexed for MEDLINE]

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