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Pediatr Dermatol. 2010 Nov-Dec;27(6):672-3.

Dental caries as a side effect of infantile hemangioma treatment with propranolol solution.

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Department of Pediatric Surgery, Virgen de la Arrixaca Children’s Hospital, Murcia, Spain.


We report the case of an 18-month-old boy who presented with caries in the upper central incisors associated with the use of propranolol solution for the treatment of an infantile hemangioma. This side effect of propranolol solution has not been reported before, and it may result from a sucrose-based excipient of the solution, or decreased salivation caused by beta-adrenergic antagonist effect of propranolol.

[Indexed for MEDLINE]

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