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Lab Chip. 2011 Jun 7;11(11):1911-5. doi: 10.1039/c0lc00706d. Epub 2011 Apr 19.

Faster multiple emulsification with drop splitting.

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School of Engineering and Applied Sciences, Department of Physics, Harvard University, Cambridge, Massachusetts, USA.


Microfluidic devices can form emulsions in which the drops have an intricate, controlled structure; however, a challenge is that the droplets are produced slowly, typically only a few millilitres per hour. Here, we present a simple technique to increase the production rate. Using a large drop maker, we produce large drops at a fast volumetric rate; by splitting these drops several times in a splitting array, we create drops of the desired small size. The advantage of this over forming the small drops directly using a small drop maker is that the drops can be formed at much faster rates. This can be applied to the production of single and multiple emulsions.

[Indexed for MEDLINE]

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