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Microb Drug Resist. 2011 Sep;17(3):425-7. doi: 10.1089/mdr.2010.0199. Epub 2011 Apr 14.

Clinical Neisseria gonorrhoeae isolates in the United States with resistance to azithromycin possess mutations in all 23S rRNA alleles and the mtrR coding region.

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1
San Francisco Department of Public Health Laboratory, San Francisco, California 94102, USA.

Abstract

We identified strains of Neisseria gonorrhoeae in San Diego County, California, that possess high levels of resistance to azithromycin (8.0-16.0 μg/ml MIC). These isolates contain a combination of mutations in both the 23S rRNA loci and mtrR genes. This is the first description of such isolates in the United States.

PMID:
21492017
DOI:
10.1089/mdr.2010.0199
[Indexed for MEDLINE]

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