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Adv Dent Res. 2011 May;23(2):237-46. doi: 10.1177/0022034511402082.

Global oral health inequalities in incidence and outcomes for oral cancer: causes and solutions.

Author information

1
Griffith Health Institute, Griffith University, Queensland, Australia. n.johnson@griffith.edu.au

Abstract

The mouth and oropharynx are among the ten most common sites affected by cancer worldwide, but global incidence varies widely. Five-year survival rates exceed 50% in only the best treatment centers. Causes are predominantly lifestyle-related: Tobacco, areca nut, alcohol, poor diet, viral infections, and pollution are all important etiological factors. Oral cancer is a disease of the poor and dispossessed, and reducing social inequalities requires national policies co-ordinated with wider health and social initiatives - the common risk factor approach: control of the environment; safe water; adequate food; public and professional education about early signs and symptoms; early diagnosis and intervention; evidence-based treatments appropriate to available resources; and thoughtful rehabilitation and palliative care. Reductions in inequalities, both within and between countries, are more likely to accrue from the application of existing knowledge in a whole-of-society approach. Basic research aimed at determining individual predisposition and acquired genetic determinants of carcinogenesis and tumor progression, thus allowing for targeted therapies, should be pursued opportunistically.

PMID:
21490236
DOI:
10.1177/0022034511402082
[Indexed for MEDLINE]

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