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Chem Commun (Camb). 2011 Jul 7;47(25):7018-24. doi: 10.1039/c1cc11021g. Epub 2011 Apr 11.

Chemistry of nucleic acids: impacts in multiple fields.

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1
Department of Chemistry, Stanford University, Stanford, CA 94305, USA.

Abstract

Research in nucleic acids has made major advances in the past decade in multiple fields of science and technology. Here we discuss some of the most important findings in DNA and RNA research in the fields of biology, chemistry, biotechnology, synthetic biology, nanostructures and optical materials, with emphasis on how chemistry has impacted, and is impacted by, these developments. Major challenges ahead include the development of new chemical strategies that allow synthetically modified nucleic acids to enter into, and function in, living systems.

PMID:
21483917
PMCID:
PMC4445425
DOI:
10.1039/c1cc11021g
[Indexed for MEDLINE]
Free PMC Article
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