Format

Send to

Choose Destination
Folia Histochem Cytobiol. 2010 Dec;48(4):597-602. doi: 10.2478/v10042-010-0078-z.

Molecular differences in the KRAS gene mutation between a primary tumor and related metastatic sites - case report and a literature review.

Author information

1
Department of Gastrointestinal Cancer, Cancer Center-Institute, Warsaw, Poland. ekosakowska@coi.waw.pl

Abstract

In recent years the the set of diagnostic tools in colorectal cancers has been extended by the assessment of the KRAS gene status. Currently it is a necessary step in order to qualify patients for the targeted therapy. The results of the analysis of several studies revealed a high rate of compliance of the KRAS gene mutational status in primary and metastatic tumors. In this paper we present a rare case of incompatibility of the KRAS mutations in the primary tumor located in the colon and metastatic changes in the liver.

PMID:
21478103
DOI:
10.2478/v10042-010-0078-z
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Via Medica Medical Publishers
Loading ...
Support Center