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Int J Pediatr Otorhinolaryngol. 2011 Jun;75(6):872-3. doi: 10.1016/j.ijporl.2011.03.006. Epub 2011 Apr 3.

Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an indication for tonsillectomy.

Author information

1
University of Virginia, Department of Radiology, Charlottesville, VA 22908, USA. aaz.alexander@yahoo.com

Abstract

Children with obsessive compulsive disorder or tic disorders that are associated with streptococcal infections (Group A beta-hemolytic) in the oro-pharyngeal region are given the diagnosis of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS). Tonsillectomy has been reported to resolve the neuro-psychiatric symptoms in these children. We have a case of a 9-year-old boy who was seen in our clinic with multiple recurrent streptococcal infections of the oro-pharyngeal cavity. He also exhibited neuro-psychiatric symptoms including agitation, hyperactivity, and tics. These symptoms followed his recurrent infections. Tonsillectomy was performed and in one year follow-up the patient did not have any recurrent streptococcal infections, and his neuro-psychiatric symptoms resolved completely. Guidelines for medical and surgical management of recurrent strep infections in the face of PANDAS are reviewed.

PMID:
21466900
DOI:
10.1016/j.ijporl.2011.03.006
[Indexed for MEDLINE]

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