Format

Send to

Choose Destination
J Cyst Fibros. 2011 Sep;10(5):318-25. doi: 10.1016/j.jcf.2011.03.006. Epub 2011 Apr 3.

Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis.

Author information

1
Department of Clinical Microbiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. christinadalboege@gmail.com

Abstract

BACKGROUND:

The clinical consequences of chronic Stenotrophomonas maltophilia infection in cystic fibrosis (CF) patient are still unclear.

METHOD:

All patients treated in the Copenhagen CF centre (N=278) from 1 January 2008 to 31 December 2009 were included. Each patient chronically infected with S. maltophilia for at least 2 years without any other chronic Gram-negative infection were matched to two non-infected CF controls.

RESULTS:

Twenty-one patients were chronically infected with S. maltophilia during the 2-year study period. Fifteen were infected for at least 2 years. The patients in the S. maltophilia group had a steeper decline (-3.2%/year vs. -0.3%/year) in FEV(1) compared to the non-infected CF controls (P=0.03). The rate of decline was the same as observed 3 years before the patients became chronically infected.

DISCUSSIONS:

Chronic infection with S. maltophilia does not lead to a steeper decline in lung function when compared to the period before chronic infection.

PMID:
21463972
DOI:
10.1016/j.jcf.2011.03.006
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center