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Ugeskr Laeger. 2011 Mar 28;173(13):968-73.

[Hereditary periodical fever syndromes].

[Article in Danish]

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Børneafdelingen, Århus Universitetshospital, Skejby, 8200 Århus N, Denmark.


Autoinflammatory diseases are characterized by attacks of apparently unprovoked inflammation without significant levels of autoantibodies or antigen-specific T-cells. Within the past decade, a number of different genetic causes of fever syndromes have been identified: familial Mediterranean fever (FMF), hyper IgD syndrome, cryopyrin-associated periodic syndromes and tumour necrosis factor receptor-associated periodic syndrome. The recent awareness and recognition of pathogenic mechanism of these diseases have led to new possibilities for medical treatment with targeted biological agents.

[Indexed for MEDLINE]

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