Format

Send to

Choose Destination
See comment in PubMed Commons below
J Neurosci. 2011 Mar 30;31(13):4792-804. doi: 10.1523/JNEUROSCI.5160-10.2011.

Orientation decoding depends on maps, not columns.

Author information

1
Center for Neural Science, New York University, New York, New York 10003, USA. freeman@cns.nyu.edu

Abstract

The representation of orientation in primary visual cortex (V1) has been examined at a fine spatial scale corresponding to the columnar architecture. We present functional magnetic resonance imaging (fMRI) measurements providing evidence for a topographic map of orientation preference in human V1 at a much coarser scale, in register with the angular-position component of the retinotopic map of V1. This coarse-scale orientation map provides a parsimonious explanation for why multivariate pattern analysis methods succeed in decoding stimulus orientation from fMRI measurements, challenging the widely held assumption that decoding results reflect sampling of spatial irregularities in the fine-scale columnar architecture. Decoding stimulus attributes and cognitive states from fMRI measurements has proven useful for a number of applications, but our results demonstrate that the interpretation cannot assume decoding reflects or exploits columnar organization.

PMID:
21451017
PMCID:
PMC3086281
DOI:
10.1523/JNEUROSCI.5160-10.2011
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center