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Am J Clin Nutr. 2011 Jun;93(6):1300-4. doi: 10.3945/ajcn.110.006544. Epub 2011 Mar 30.

Breast-milk intake of 9-10-mo-old rural infants given a ready-to-use complementary food in South Kivu, Democratic Republic of Congo.

Author information

1
Valid Nutrition, Nairobi, Kenya. victor@validnutrition.org

Abstract

BACKGROUND:

Lipid-based ready-to-use foods are currently used for infant feeding, but their potential effect on breast-milk intake is not well documented.

OBJECTIVE:

The objective was to assess the breast-milk intake of 9-10-mo-old infants given either a ready-to-use complementary food (RUCF) paste or a standard corn-soy blend (UNIMIX) porridge in South Kivu, Democratic Republic of Congo.

DESIGN:

Infants were randomly assigned at 6 mo of age to receive either RUCF (n = 700) or UNIMIX (n = 700) for 6 mo. Breast-milk intake was measured at 9-10 mo in a subsample of 58 infants (29 from each group). Mothers received a dose of ≈30 g deuterium oxide. Predose and postdose saliva samples were collected from both mothers and infants over 2 wk. Breast-milk intake (g/d) was measured from saliva samples by using infrared spectroscopy.

RESULTS:

Mean (±SD) breast-milk intake was not significantly (P = 0.69) different between the 2 groups: RUCF (705 ± 236 g/d) and UNIMIX (678 ± 285 g/d). Mean (±SD) nonmilk oral water intakes were 338.3 ± 251.1 and 336.4 ± 227.2 g/d for RUCF and UNIMIX, respectively (P = 0.98).

CONCLUSIONS:

No differences in breast-milk intake were observed between infants consuming either RUCF or UNIMIX. The deuterium-dose-to-the-mother dilution technique is an affordable technique that we recommend for periodic evaluation of breast-milk intake in resource-poor settings. This trial is registered at controlled-trials.com as ISRCTN20267635.

PMID:
21450933
DOI:
10.3945/ajcn.110.006544
[Indexed for MEDLINE]

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