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J Gastroenterol Hepatol. 2011 Aug;26(8):1283-9. doi: 10.1111/j.1440-1746.2011.06726.x.

Prevalence and determinants of Helicobacter pylori sero-positivity in the Australian adult community.

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1
School of Population Health, the University of Queensland, Australia. n.pandeya1@uq.edu.au

Abstract

BACKGROUND AND AIM:

  To estimate the sero-prevalence of Helicobacter Pylori infection in the Australian adult population and identify determinants.

METHODS:

  We analyzed serum samples and questionnaire data from 1355 community controls who participated in a nationwide case-control study of esophageal cancer in Australia between 2002 and 2005. We estimated the prevalence ratio and 95% confidence interval using log binomial regression models.

RESULTS:

  The age and sex standardized sero-prevalence of H. pylori was 15.5%. The prevalence of infection varied significantly with age, ranging from 5% (< 40 years) to 32% (≥ 70 years). H. pylori infection was significantly higher among those born overseas (prevalence ratio [PR] 1.63; 95% confidence interval [CI] 1.34-1.98) compared with those born in Australia or New Zealand. H. pylori sero-prevalence was 23% higher among participants living in the lowest quartile of socio-economic areas (PR 0.77; 95%CI 0.59-0.99 for Q4 compared with Q1). H pylori serostatus was significantly inversely associated with university education (PR 0.56; 95%CI 0.38-0.83), frequent reflux symptoms (PR 0.62; 95%CI 0.42-0.91), use of proton pump inhibitor (PR 0.69; 95%CI 0.48-0.98) and use of medications for gut spasms (PR 0.48; 95%CI 0.25-0.93). H. pylori serostatus was not associated with body mass index, smoking, alcohol or physical activity.

CONCLUSIONS:

  The prevalence of H. pylori infection in Australian adults is lower than other developed countries. H. pylori infection is most common among those living in the areas of socio-economic disadvantage or who were born overseas.

[Indexed for MEDLINE]

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