Introduction: Till 1963 vaccinations against biological agents are mandatory for street cleaners and workers employed in the service of rubbish collection in Italy.
Materials and methods: The principal ways to choose the specific and useful vaccine against the potential biological risk are: 1) To make a careful risk assessment--having the knowledge of fixtures and fittings and 2) To analize the injuries story along the time.
Results: No cases of seroconversion showed (1999-2008) in ten years of control in a big public company located in North of Italy where the choice of vaccine for every kind of task is made in reason of the really risk.
Conclusions: We have to play attention on a new kind of problems that's growing in West Countries managing active immunisation: a) workers coming from every side of the world with or without vaccinal protection and b) workers old, ill, with natural or illness caused immunodeficiency.