Format

Send to

Choose Destination
See comment in PubMed Commons below
Pan Afr Med J. 2010 Jul 28;6:4.

Neuroendocrine differentiation in a case of cervical cancer.

Author information

1
Department of Pathology, Damanhour National Medical Institute, General Organization of Teaching Hospitals and Institutes, Egypt.

Abstract

Neuroendocrine neoplasms may occur in the uterine cervix, although rarely; it accounts for 0.5-1% of all malignant tumors of the uterine cervix. A case report of an Ethiopian female presented at the Gynecology Out-Patient Clinic at Jimma University Hospital, complaining from irregular vaginal bleeding over the previous three months. Clinically there was a cauliflower cervical mass; histopathologically it was formed of sheets of small cell tumor; that further showed neuroendocrine differentiation, as demonstrated by chromogranin-A positivity. It is important to differentiate small cell carcinoma from other malignant tumors of the uterine cervix. Morphological features play an important role in making a diagnosis and the immunohistochemistry study can offer an additional useful assistance.

KEYWORDS:

Cervical cancer; cervix; chromogranine A; small cell carcinoma

PMID:
21436947
PMCID:
PMC3063496
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Pan African Medical Journal Icon for PubMed Central
    Loading ...
    Support Center