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Diabetes Care. 2011 May;34(5):1089-90. doi: 10.2337/dc10-2149. Epub 2011 Mar 23.

Basal insulin requirement is ~30% of the total daily insulin dose in type 1 diabetic patients who use the insulin pump.

Author information

1
Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan. kurodaakio@gmail.com

Abstract

OBJECTIVE:

To investigate the basal insulin requirement in total daily insulin dose in Japanese type 1 diabetic patients who use the insulin pump.

RESEARCH DESIGN AND METHODS:

The basal insulin requirement in 35 type 1 diabetic patients without detectable C-peptide using the insulin pump (Paradigm 712) was investigated during 2-3 weeks of hospitalization. The patients were served diabetic diets of 25-30 kcal/kg ideal body weight. Each meal omission was done to confirm stable blood glucose levels within 30 mg/dL variance until the next meal. Target blood glucose level was set at 100 mg/dL before each meal and 150 mg/dL at 2 h after each meal.

RESULTS:

Total daily insulin dose was 31.6 ± 8.5 units, and total basal insulin requirement was 8.7 ± 2.9 units, which was 27.7 ± 6.9% of the total daily dose.

CONCLUSIONS:

Basal insulin requirement is ~30% of the total daily dose in Japanese type 1 diabetic patients who use the insulin pump.

PMID:
21430086
PMCID:
PMC3114495
DOI:
10.2337/dc10-2149
[Indexed for MEDLINE]
Free PMC Article
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