Format

Send to

Choose Destination
Clin Infect Dis. 2011 Apr 1;52(7):925-8. doi: 10.1093/cid/cir072.

Reanalysis of coreceptor tropism in HIV-1-infected adults using a phenotypic assay with enhanced sensitivity.

Author information

1
Division of Infectious Disease, Weill Cornell Medical College, New York, New York 10011, USA. tiw2001@med.cornell.edu

Abstract

The enhanced-sensitivity Trofile assay (TF-ES; Monogram Biosciences) was used to retest coreceptor tropism samples from 4 different cohorts of HIV-1-infected patients. Nine percent to 26% of patients with CCR5-tropic virus by the original Trofile assay had CXCR4-using virus by TF-ES. Lower CD4 cell counts were associated with CXCR4-using virus in all cohorts.

PMID:
21427401
PMCID:
PMC3106234
DOI:
10.1093/cid/cir072
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Silverchair Information Systems Icon for PubMed Central
Loading ...
Support Center