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J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2011;29(1):1-31. doi: 10.1080/10590501.2011.551317.

Dietary flavonoids as cancer prevention agents.

Author information

1
Department of Stomatology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Abstract

Dietary agents identified from fruits and vegetables contribute to keeping balanced cell proliferation and preventing cell carcinogenesis. Dietary flavonoids, combined with other components such as various vitamins, play an important role in cancer prevention. Flavonoids act on reactive oxygen species, cell signal transduction pathways related to cellular proliferation, apoptosis, and angiogenesis. Many studies demonstrate that flavonoids are responsible for chemoprevention, although mechanisms of action remain to be investigated. Overall, exciting data show that dietary flavonoids could be considered as a useful cancer preventive approach. This review summarizes recent advancements on potential cancer preventive effects and mechanic insight of dietary flavonoids.

PMID:
21424974
DOI:
10.1080/10590501.2011.551317
[Indexed for MEDLINE]

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