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Int Urogynecol J. 2011 Jul;22(7):789-98. doi: 10.1007/s00192-011-1384-5. Epub 2011 Mar 22.

Incidence and management of graft erosion, wound granulation, and dyspareunia following vaginal prolapse repair with graft materials: a systematic review.

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1
Department Obstetrics & Gynecology, Henry Ford Health System, 3031 West Grand Blvd. 8th Floor, Detroit, MI 48202, USA. habed2@hfhs.org

Abstract

INTRODUCTION AND HYPOTHESIS:

This study describes the incidence, risk factors, and treatments of graft erosion, wound granulation, and dyspareunia as adverse events following vaginal repair of pelvic organ prolapse with non-absorbable synthetic and biologic graft materials.

METHODS:

A systematic review in Medline of reports published between 1950 and November 2010 on adverse events after vaginal prolapse repairs using graft materials was carried out.

RESULTS:

One hundred ten studies reported on erosions with an overall rate, by meta-analysis, of 10.3%, (95% CI, 9.7 - 10.9%; range, 0 - 29.7%; synthetic, 10.3%; biological, 10.1%). Sixteen studies reported on wound granulation for a rate of 7.8%, (95% CI, 6.4 - 9.5%; range, 0 - 19.1%; synthetic, 6.8%; biological, 9.1%). Dyspareunia was described in 70 studies for a rate of 9.1%, (95% CI, 8.2 - 10.0%; range, 0 - 66.7%; synthetic, 8.9%; biological, 9.6%).

CONCLUSIONS:

Erosions, wound granulation, and dyspareunia may occur after vaginal prolapse repair with graft materials, though rates vary widely across studies.

PMID:
21424785
DOI:
10.1007/s00192-011-1384-5
[Indexed for MEDLINE]

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