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Obstet Gynecol. 2011 Apr;117(4):883-5. doi: 10.1097/AOG.0b013e3182107d47.

Urine screening for Chlamydia trachomatis during pregnancy.

Author information

1
Department of Obstetrics and Gynecology, the University of Texas Southwestern Medical Center, Dallas, Texas 75235-9032, USA. scott.roberts@utsouthwestern.edu

Abstract

OBJECTIVE:

To compare the rates of Chlamydia trachomatis detection using urine and cervical secretions from pregnant women at our institution.

METHODS:

A large cross-sectional sample of pregnant women (N=2,018) at 35-37 weeks of gestation were tested for C trachomatis with both endocervical and urine sampling using the Aptima Combo 2 Assay.

RESULTS:

A prevalence of 4.3% and 4.1% were found for Chlamydia endocervical and urine samples, respectively. There was no difference between the two tests by McNemar's test (-0.02%, 0.32%; P=.083). There was excellent correlation between the tests found by the κ statistic (0.982 [0.961-1.000]).

CONCLUSION:

Urine sampling for C trachomatis is equivalent to endocervical sampling in pregnancy using the Aptima 2 Combo Assay.

LEVEL OF EVIDENCE:

II.

PMID:
21422860
DOI:
10.1097/AOG.0b013e3182107d47
[Indexed for MEDLINE]

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