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Pediatr Infect Dis J. 2011 Sep;30(9):799-801. doi: 10.1097/INF.0b013e318216dbab.

Waning immunity to varicella in infants of human immunodeficiency virus-seropositive and -seronegative mothers.

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1
Department of Pediatrics, Meharry Medical College, Nashville, TN, USA. schoudhury@mmc.edu

Abstract

Immunity to varicella in HIV-exposed and -unexposed infants born to unvaccinated mothers, acquiring protective antibodies at birth declined to nonprotective (<1:8) levels by 5 months of age. Therefore, infants become susceptible to varicella before 12 months, which is the recommended time for varicella immunizations in the United States. Vaccination of susceptible HIV-seronegative women in the postpartum period may be important to consider.

PMID:
21412180
PMCID:
PMC3158244
DOI:
10.1097/INF.0b013e318216dbab
[Indexed for MEDLINE]
Free PMC Article
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