Format

Send to

Choose Destination
Genes Dev. 2011 Mar 15;25(6):529-33. doi: 10.1101/gad.2038611.

RNAi genes pave their own way.

Author information

1
Hubrecht Institute-KNAW, University Medical Centre Utrecht, 3584 CT Utrecht, The Netherlands. r.ketting@hubrecht.eu

Abstract

Heterochromatin formation in fission yeast and the role of RNAi in this process have been intensively studied. So far, however, nothing is known about the regulation of expression of RNAi components during these events. Gullerova and colleagues (pp. 556-568) reveal an autoregulatory loop that regulates the expression of RNAi genes and centromeric heterochromatin formation during the cell cycle. Gene orientation plays a surprising role in this process.

PMID:
21406552
PMCID:
PMC3059828
DOI:
10.1101/gad.2038611
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center