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Infect Disord Drug Targets. 2011 Apr;11(2):98-114.

Targeting HIV: past, present and future.

Author information

1
Department of Internal Medicine (Infectious Diseases), University of Stellenbosch and Tygerberg Hospital, Parow 7505, Cape Town, South Africa. mdz@sun.ac.za

Abstract

Since the identification of the human immunodeficiency virus (HIV) as the cause of the syndrome of acquired immunodeficiency syndrome (AIDS), there has been an evolution of compounds targeting the replication of the virus in an effort to delay clinical progression. In this review, we revise the mechanism of action of the different groups of drugs. We shortly revisit the older and perhaps lesser used as well as the more recently approved drugs and mention some of the compounds still under investigation.

PMID:
21406054
DOI:
10.2174/187152611795589690
[Indexed for MEDLINE]

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