Format

Send to

Choose Destination
Muscle Nerve. 2011 May;43(5):751-5. doi: 10.1002/mus.21974. Epub 2011 Mar 14.

Value of distal compound muscle action potential duration prolongation in acute inflammatory demyelinating polyneuropathy: a European perspective.

Author information

1
Neuromuscular Clinic, Department of Neurology, University Hospitals of Leicester, Leicester General Hospital, Leicester LE5 4PW, UK. yusuf.rajabally@uhl-tr.nhs.uk

Abstract

INTRODUCTION:

The value of distal compound muscle action potential duration (DCMAPD) has not been widely studied in acute inflammatory demyelinating polyneuropathy (AIDP) with electromyography (EMG) equipment at low-cut filter settings <10 Hz, as used in Europe.

METHODS:

We retrospectively reviewed the records of 40 patients with AIDP and 40 controls with axonal neuropathy, from Leicester, UK, and Angers, France.

RESULTS:

The best combination of sensitivity/specificity for AIDP using DCMAPD prolongation in any one nerve was offered by cut-offs from two other studies (sensitivity: 90% and 87.5%, respectively; specificity: 92.5% for both). Independent DCMAPD prolongation in any one nerve was better than, or equivalent to, other criteria.

CONCLUSIONS:

DCMAPD prolongation in any one nerve, at cut-offs suggested by prior studies, represents a sensitive and specific marker to aid/simplify electrodiagnosis of AIDP in patients studied with EMG equipment with low-cut filter settings of <10 Hz.

PMID:
21404299
DOI:
10.1002/mus.21974
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center