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Cardiovasc Clin. 1990;20(3):85-94.

Left ventricular hypertrophy: an independent factor of risk.


Left ventricular hypertrophy imposes a definite risk of increased cardiovascular morbidity and mortality. This increased risk is independent of other risks (including that of hypertension). The precise mechanism or mechanisms that account for this risk are not known, although several possible factors have been identified. A variety of antihypertensive agents have been shown to decrease the mass of hypertrophied left ventricle, although some may also diminish the mass of the normal ventricle. No study to date has demonstrated improvement in the risk from LVH with so-called reversal of LVH with pharmacologic agents.

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