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Cephalalgia. 2011 Jul;31(10):1082-9. doi: 10.1177/0333102411398155. Epub 2011 Mar 11.

Headache outcomes following treatment of unruptured intracranial aneurysms: a prospective analysis.

Author information

1
Washington University School of Medicine, USA. schwedtt@neuro.wustl.edu

Abstract

OBJECTIVE:

To analyze headache patterns prior to and following treatment of unruptured intracranial aneurysms and identify factors associated with different headache outcomes.

METHODS:

A prospective observational study of patients being treated for unruptured intracranial aneurysms. Headache patterns were established prior to aneurysm treatment and for 6 months following treatment. Factors associated with different headache outcomes were investigated.

RESULTS:

In all patients (n = 44), 90-day headache frequency decreased from an average of 31 days prior to aneurysm treatment to 17 days following treatment (p < 0.001). In patients with active pretreatment headaches (n = 28), 90-day headache frequency decreased from 49 days to 26 days (p = 0.002). Headache frequency was reduced in 68% of patients, while 9% of patients had new or worsened headaches following aneurysm treatment. Pretreatment migraine, more severe pretreatment headaches, higher pretreatment trait anxiety, and stent-assisted aneurysm coiling were associated with a lack of headache improvement.

CONCLUSIONS:

The majority of patients with headaches at the time of aneurysm treatment had reductions in headache frequency during the 6 months following treatment. Potential risk factors for poor headache outcomes were identified but need to be studied further.

PMID:
21398420
PMCID:
PMC3593349
DOI:
10.1177/0333102411398155
[Indexed for MEDLINE]
Free PMC Article
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