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Bioorg Med Chem Lett. 2011 Apr 15;21(8):2554-8. doi: 10.1016/j.bmcl.2011.02.004. Epub 2011 Feb 17.

Identification and optimization of tetrahydro-2H-3-benzazepin-2-ones as squalene synthase inhibitors.

Author information

1
Bayer Pharma AG, Global Drug Discovery, Medicinal Chemistry Wuppertal, Building 460, D-42096 Wuppertal, Germany. nils.griebenow@bayer.com

Abstract

Novel squalene synthase inhibitors are disclosed. SAR and pharmacological profile of selected compounds are discussed.

PMID:
21396815
DOI:
10.1016/j.bmcl.2011.02.004
[Indexed for MEDLINE]

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