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Diagn Microbiol Infect Dis. 2011 Apr;69(4):460-2. doi: 10.1016/j.diagmicrobio.2010.11.002.

Evaluation of the Xpert® group B streptococcus real-time polymerase chain reaction assay compared to StrepB Carrot Broth™ for the rapid intrapartum detection of group B streptococcus colonization.

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Calgary Laboratory Services, Calgary Health Region and the University of Calgary, Calgary, T2L 2K8 Alberta, Canada.


Xpert group B streptococcus (GBS) was compared to StrepB Carrot Broth™ (SCB) for the detection of intrapartum GBS colonization by dually collecting vaginal/rectal swabs from 231 women. Xpert GBS detected all of the cases (45, 19.5%), but 4 were missed by SCB. A rapid Xpert GBS service for women in labor would increase costs by ∼$55.000 per annum in our region.

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