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Managing scleromyxedema with intravenous immunoglobulin: acute worsening of scleromyxedema with biclonal gammopathy.

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1
Department of Dermatology, Venereology, and Allergology, Mannheim University Hospital, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, Mannheim, Germany. ioannis.manousaridis@umm.de

Abstract

Scleromyxedema is a rare chronic cutaneous mucinosis usually associated with a monoclonal gammopathy and underlying systemic disease. The etiology of the disease is not known. There are no standard treatments and response to various therapeutic modalities varies. We report a case of refractory scleromyxedema in a 63-year-old man with a biclonal IgG and IgM λ-gammopathy. The patient was successfully managed with intravenous immunoglobulin.

PMID:
21390475
[Indexed for MEDLINE]
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