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Cornea. 2011 Aug;30(8):889-94. doi: 10.1097/ICO.0b013e3182041fd3.

Investigation of femtosecond laser--enabled keratoplasty wound geometry using optical coherence tomography.

Author information

1
Center for Ophthalmic Optics and Lasers, Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA.

Abstract

PURPOSE:

To measure the wound geometry after femtosecond laser-enabled keratoplasty (FLEK) using optical coherence tomography (OCT).

DESIGN:

Prospective nonrandomized clinical study and laboratory study.

PARTICIPANTS:

Patients who were candidates for penetrating keratoplasty at an academic referral center.

METHODS:

Wound architecture was measured and analyzed by OCT in 8 eyes of 8 consecutive patients who underwent FLEK. Femtosecond laser lamellar cuts were performed on 3 eye bank corneas, and the wound diameters were measured by OCT.

RESULTS:

Sutures were completely removed on average at 1 month per decade of age after surgery. No cases of wound dehiscence were noted, and graft-host tissue apposition appeared excellent on OCT. The mean spectacle-corrected visual acuity 1 month after suture removal was 20/35, and mean astigmatism was 5.0 diopters by manifest refraction and 8.7 diopters by computerized topography. The measured graft diameter was smaller than the laser setting by 2.5% (P = 0.007). The cut diameters of the eye bank corneas were also slightly smaller than the laser setting.

CONCLUSIONS:

FLEK offers benefits of rapid wound healing and predictable wound geometry. The measured wound geometry agreed well with laser setting other than a small systematic deviation that could be explained by the mechanics of corneal applanation during the laser cut. OCT is a useful tool to measure the actual graft diameter after FLEK.

PMID:
21389851
DOI:
10.1097/ICO.0b013e3182041fd3
[Indexed for MEDLINE]
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