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Cytokine Growth Factor Rev. 2011 Apr;22(2):73-81. doi: 10.1016/j.cytogfr.2011.02.002. Epub 2011 Mar 8.

Matrix metalloproteinase8 has a central role in inflammatory disorders and cancer progression.

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1
Department for Molecular Biomedical Research, VIB, Ghent, Belgium.

Abstract

The predominant role of matrix metalloproteinase 8 in extracellular matrix turnover, modulation of inflammatory responses and other physiological processes is well documented. Several recent studies highlight the involvement of MMP8 in a wide range of pathologies. This review will shed light on the putative role of MMP8 as a drug target or disease marker in some inflammatory disorders and in cancer progression.

PMID:
21388856
DOI:
10.1016/j.cytogfr.2011.02.002
[Indexed for MEDLINE]

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