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Neuron. 2011 Mar 10;69(5):856-75. doi: 10.1016/j.neuron.2011.02.032.

Mechanisms and function of dendritic exocytosis.

Author information

1
Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA. kennedy@neuro.duke.edu

Abstract

Dendritic exocytosis is required for a broad array of neuronal functions including retrograde signaling, neurotransmitter release, synaptic plasticity, and establishment of neuronal morphology. While the details of synaptic vesicle exocytosis from presynaptic terminals have been intensely studied for decades, the mechanisms of dendritic exocytosis are only now emerging. Here we review the molecules and mechanisms of dendritic exocytosis and discuss how exocytosis from dendrites influences neuronal function and circuit plasticity.

PMID:
21382547
PMCID:
PMC3073864
DOI:
10.1016/j.neuron.2011.02.032
[Indexed for MEDLINE]
Free PMC Article

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