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Pathol Res Pract. 2011 Apr 15;207(4):253-5. doi: 10.1016/j.prp.2010.10.002. Epub 2011 Mar 3.

Primary mixed mullerian tumor of the vagina--a case report with review of the literature.

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Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.


Malignant mixed mullerian tumor (MMMT) is a rare entity. The commonest site of this tumor in the female genital tract is the uterus followed by cervix. Primary MMMT of vagina is extremely rare. We are reporting this rare entity, with a brief review of the literature, in a 48-year-old perimenopausal female who presented with a history of passage of urine per vagina. On pelvic examination, a polypoidal mass arising from the anterior wall of the vagina was identified. Histopathological examination revealed the biphasic nature of the tumor. Immunohistochemistry confirmed the diagnosis of MMMT of vagina. To conclude, although rare, clinicians, oncologists, and pathologists should identify this malignant tumor for appropriate treatment and management.

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