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Dermatol Clin. 1990 Jan;8(1):161-4.

Reactions to thimerosal in hepatitis B vaccines.

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Department of Dermatology, Ochsner Clinic, New Orleans, Louisiana.


Hypersensitivity to thimerosal in vaccines has been reported to induce persistent local reactions, urticarial and generalized exanthematic eruptions, and, in the case of the hepatitis B vaccine, urticaria with asthma. The authors describe two cases of extensive reactions, one in a patient who did not form antibodies to the principal vaccine antigen. Although not all thimerosal-sensitive patients develop adverse reactions to vaccines containing this material, there is a potential risk, and the reactions can be very long lasting.

[Indexed for MEDLINE]

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