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Bioinformatics. 2011 Apr 1;27(7):1039-40. doi: 10.1093/bioinformatics/btr054. Epub 2011 Mar 3.

ncIDP-assign: a SPARKY extension for the effective NMR assignment of intrinsically disordered proteins.

Author information

1
Department of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands. k.tamiola@rug.nl

Abstract

We describe here the ncIDP-assign extension for the popular NMR assignment program SPARKY, which aids in the sequence-specific resonance assignment of intrinsically disordered proteins (IDPs). The assignment plugin greatly facilitates the effective matching of a set of connected resonances to the correct position in the sequence by making use of IDP random coil chemical shifts.

AVAILABILITY:

The ncIDP-assign extension is available at http://www.protein-nmr.org/.

PMID:
21372082
PMCID:
PMC3065690
DOI:
10.1093/bioinformatics/btr054
[Indexed for MEDLINE]
Free PMC Article
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