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Epidemiol Infect. 2012 Jan;140(1):74-7. doi: 10.1017/S0950268811000240. Epub 2011 Mar 4.

Seasonal pattern and genotype distribution of sapovirus infection in Japan, 2003-2009.

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Department of Developmental Medical Sciences, Institute of International Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.


Sapovirus, a member of the family Caliciviridae, is one of the major causative agents of viral gastroenteritis affecting all age groups. A total of 3232 faecal specimens collected from infants and children with gastroenteritis in five different regions of Japan during 2003-2009 were examined for sapovirus by reverse transcription-polymerase chain reaction. Sapoviruses were detected in 131 (4ยท05%) patients with the peak observed mainly in the cold season (November-March) in Japan during 2003-2009. During the last 6 years, sapovirus GI/1 was the predominant strain in Japan followed by GIV, GII/3, GII/6, GII/2, GII/12 and GI, respectively.

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