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Pediatr Dermatol. 2011 May-Jun;28(3):349-50. doi: 10.1111/j.1525-1470.2011.01234.x. Epub 2011 Mar 3.

Recalcitrant palmoplantar pustular psoriasis treated with etanercept.

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Department of Dermatology, La Paz University Hospital, Madrid, Spain.


We report a 10-year-old boy presenting with palmoplantar pustular psoriasis, resistant to topical and systemic treatments, who was successfully treated with subcutaneous etanercept (0.4 mg/kg) twice a week for 1 month. Maintenance therapy was extended for 18 months in combination with near ultraviolet light therapy without any adverse effect. Etanercept may be a safe and effective alternative for severe palmoplantar pustular psoriasis in children.

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