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Am J Surg. 2011 Mar;201(3):406-10; discussion 410. doi: 10.1016/j.amjsurg.2010.09.023.

Support for a postresection prognostic score for pancreatic endocrine tumors.

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1
Department of Surgery, Division of Surgical Oncology, Loyola University Medical Center, Maywood, IL 60153, USA.

Abstract

BACKGROUND:

Prognostic scores predicting long-term survival of patients with pancreatic neuroendocrine tumors (PNETs) have been created. The purpose of this study was to validate a prognostic scoring scheme at a single institution.

METHODS:

We reviewed all resections for PNETs from 1996 to 2004. Prognostic scores based on patient age, tumor grade, and distant metastasis were calculated. Survival was compared with an established postresection prognostic score for PNETs.

RESULTS:

A total of 34 PNETs were identified. Predicted 5-year survival for prognostic scores of 1, 2, and 3 were 76.7%, 50.9%, and 35.7%, respectively. Final prognostic scores of 1, 2, and 3 were observed in 13 (38%), 18 (53%), and 3 (9%) patients, with observed actual 5-year survivals of 92.3%, 72.2%, and 66.7%, respectively.

CONCLUSIONS:

PNET prognostic scores were found to be inversely related to survival. PNET postresection prognostic score categories may be useful tools in predicting long-term survival.

PMID:
21367388
DOI:
10.1016/j.amjsurg.2010.09.023
[Indexed for MEDLINE]
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