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Arch Pathol Lab Med. 2011 Mar;135(3):317-20. doi: 10.1043/2009-0382-RA.1.

Atypical genital nevus.

Author information

1
Department of Pathology, Western General Hospital, National Health Service Lothian University Hospitals Trust, University of Edinburgh, Scotland. t_brenn@yahoo.com

Abstract

CONTEXT:

Atypical genital nevus is rare and the only poorly documented melanocytic lesion in the spectrum of nevi of special sites. It is characterized by unique and reproducible histologic features, which may appear alarming and may raise significant concern for a diagnosis of melanoma.

OBJECTIVES:

To present the clinical and histologic features of atypical genital nevus with emphasis on distinction from vulvar melanoma.

DATA SOURCES:

The findings are based on a review of the current literature.

CONCLUSIONS:

Atypical genital nevus is most often found in the vulva of premenopausal women. Despite the alarming histologic features, its clinical behavior appears benign with only rare local recurrence after incomplete removal. Recognition of this unusual melanocytic lesion and its characteristic histologic features is important to avoid overdiagnosis of invasive melanoma, with subsequent wide excision or sentinel lymph node biopsy, especially in view of the sensitive anatomic location.

PMID:
21366454
DOI:
10.1043/2009-0382-RA.1
[Indexed for MEDLINE]
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