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Chem Commun (Camb). 2011 May 7;47(17):4887-9. doi: 10.1039/c0cc05713d. Epub 2011 Feb 28.

Reactive oxygen species in photochemistry of the red fluorescent protein "Killer Red".

Author information

1
School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA.

Abstract

The fluorescent protein aptly named "Killer Red" (KRed) is capable of killing transfected cells and inactivating fused proteins upon exposure to visible light in the presence of oxygen. We have investigated the source of the bioactive species through a variety of photophysical and photochemical techniques. Our results indicate a Type I (electron transfer mediated) photosensitizing mechanism.

PMID:
21359336
DOI:
10.1039/c0cc05713d
[Indexed for MEDLINE]

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