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Pediatr Infect Dis J. 2011 Aug;30(8):721-3. doi: 10.1097/INF.0b013e31820fc6e3.

Pneumocystis jiroveci pneumonia in an infant with severe folate deficiency.

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1
Department of Haematology, Royal Children's Hospital Melbourne, Parkville, Victoria, Australia.

Abstract

Pneumocystis jiroveci pneumonia is rare in immunocompetent children. Severe folate deficiency affects T cell function, potentially increasing susceptibility to opportunistic pathogens. We report the case of an 11-month-old child who developed P. jiroveci pneumonia in the setting of severe nutritional folate deficiency and review the literature regarding the influence of folate on immunity.

PMID:
21346686
DOI:
10.1097/INF.0b013e31820fc6e3
[Indexed for MEDLINE]
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